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University of Graz Natural sciences News Gemeinsame Gründung
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Wednesday, 26 April 2017

Gemeinsame Gründung

Uni Graz und TU Graz bauen aus: In einem neuen Research Studio, das ab 1. Mai 2017 startet, sollen Forschungen zu Stoffwechselerkrankungen vorangetrieben wird und Medikamente entwickelt werde. Foto: Uni Graz/Lunghammer ©Uni Graz/Lunghammer

Uni Graz und TU Graz bauen aus: In einem neuen Research Studio, das ab 1. Mai 2017 startet, sollen Forschungen zu Stoffwechselerkrankungen vorangetrieben wird und Medikamente entwickelt werde. Foto: Uni Graz/Lunghammer

Uni Graz und TU Graz bauen in Zukunft die Erforschung von Stoffwechselerkrankungen weiter aus

Weltweit sind rund 1,9 Milliarden Menschen übergewichtig. 75 Prozent darunter leiden unter einer nicht-alkoholischen Fettleber, 400 Millionen haben Typ-II-Diabetes. Verursacht werden die Erkrankungen durch einen erhöhten Fettsäurespiegel im Blut. Der Wirkstoff Atglistatin kann diesen nachweislich reduzieren, wie eine Grazer Forschungsgruppe der Universität Graz und TU Graz kürzlich herausgefunden hat. Die WissenschafterInnen Univ.-Prof. Dr. Rudolf Zechner, Assoz.-Prof. Dr. Robert Zimmermann, beide Uni Graz, und Univ.-Prof. Dr. Rolf Breinbauer von der TU Graz konnten Atglistatin synthetisch herstellen. Ihre Ergebnisse publizierten sie dazu im März 2017 im renommierten Fachmagazin Nature Communications. Sie gehen seit Jahren der Entstehung von stoffwechselbedingten Erkrankungen, die mit Adipositas in Verbindung gebracht werden, auf den Grund.

Nun hat es diese Grundlagenforschung geschafft, fit für den Markt zu werden: An der Uni Graz und TU Graz entsteht unter dem Namen „Preclinical development of small molecule inhibitors targeting human adipose triglyceride lipase“ in den kommenden zwei Jahren ein Spin-off-Unternehmen. Im Rahmen dessen soll der Wirkstoff Atglistatin für den humanen Einsatz weiterentwickelt und zum Patent gebracht werden. Ziel ist es letztendlich ein wirksames Medikament für Erkrankungen wie Fettleber oder Diabetes Typ II auf den Markt zu bringen. Das Spin-off wird als „Research Studio“ von der Österreichischen Forschungsgesellschaft FFG mit insgesamt 1,2 Millionen Euro gefördert. Research Studios sind Forschungseinheiten, die in Österreich an Institutionen, wie etwa Hochschulen, angedockt sind. In diesem Jahr wurden elf genehmigt, 46 wurden beantragt. Starten soll das Grazer Research Studio zur Erforschung von Stoffwechselerkrankungen am 1. Mai 2017.

Diese Spin-off-Gründung ist nicht nur ein weiteres Beispiel für die erfolgreiche Kooperation NAWI Graz zwischen der Karl-Franzens-Universität Graz und der TU Graz in den Naturwissenschaften, sondern zeigt, wie universitäre Grundlagenforschung in ein Hightech-Unternehmen münden kann.

Weitere Information zur Publikation unter https://on.uni-graz.at/de/detail/article/schutz-schalter/ 

created by Konstantinos Tzivanopoulos

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Sustainability Award 2024 for two projects of the University of Graz

How do major international conferences reduce their carbon footprint? And what can maths lessons contribute to education for sustainable development? Two questions that were answered at the University of Graz. The corresponding projects were awarded the Sustainability Award 2024 in silver on 26 November in Vienna. This award for Austria's universities and colleges is presented by the Ministry of Science and the Ministry of Climate Protection.

Bees under observation: University of Graz provides unprecedented insights into the hive

What is going on in the combs? How many eggs is the queen laying? How much honey is there? Autonomous robots and AI algorithms provide important data and high-resolution real-time images from inside a beehive. "As part of an international team, we have developed a game-changer technology for a new type of digitalised behavioural research," reports biologist Thomas Schmickl from the Artifical Life Lab at the University of Graz. The publication, which has just appeared as the cover story in the journal "Science Robotics", describes the wealth of information that can be obtained from this unique research facility.

Research for healthy aging: FWF funds Cluster of Excellence "MetAGE" with 18 million euros

Six researchers from the Field of Excellence "BioHealth" at the University of Graz, together with colleagues from the Medical Universities of Graz and Vienna, have acquired an FWF-funded "Cluster of Excellence". Now a newly formed center of excellence will be created under the leadership of the University of Graz. The aim is to gain a better understanding of healthy aging. The findings will flow directly into clinical research.

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